Corticosteroid-sparing effect of tacrolimus in the initial treatment of dermatomyositis and polymyositis.

Abstract

OBJECTIVE In the treatment of polymyositis (PM) and dermatomyositis (DM), muscle inflammation and underlying autoimmunity need to be suppressed promptly; however, catabolic effects of corticosteroids such as myopathy can be detrimental in PM/DM. In this study, we aimed to assess the corticosteroid-sparing effect of tacrolimus in the initial treatment of PM… (More)
DOI: 10.3109/14397595.2015.1029239

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