Corticosteroid receptors in liver cytosol of the clawed toad, Xenopus laevis: daily and seasonal variations.

@article{Lange1988CorticosteroidRI,
  title={Corticosteroid receptors in liver cytosol of the clawed toad, Xenopus laevis: daily and seasonal variations.},
  author={Catalina Lange and Wilfried Hanke},
  journal={General and comparative endocrinology},
  year={1988},
  volume={71 1},
  pages={141-52}
}
In postmetamorphic Xenopus laevis liver cytosol the glucocorticoid binding capacity R0 and the dissociation constant Kd were determined. The receptor assay included an incubation period of 24 hr at 0-4 degrees with sodium molybdate to stabilize the receptor. Dexamethasone, triamcinolone acetonide, and corticosterone as tritiated ligands were compared regarding the R0 (67.6, 57.2, and 30.7 fmol/mg protein), the Kd (3.54, 0.56, and 9.03 nM), and the rate of dissociation in young specimens of X… CONTINUE READING

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