Corticospinal system development depends on motor experience.

  title={Corticospinal system development depends on motor experience.},
  author={John H Martin and Michelle Choy and Seth L Pullman and Zhuo Meng},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={24 9},
Early motor experiences have been shown to be important for the development of motor skills in humans and animals. However, little is known about the role of motor experience in motor system development. In this study, we address the question of whether early motor experience is important in shaping the development of the corticospinal (CS) tract. We prevented limb use by the intramuscular injection of botulinum toxin A into selected forelimb muscles to produce muscle paralysis during the… CONTINUE READING


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