Corticolimbic brain reactivity to social signals of threat before and after sertraline treatment in generalized social phobia.

@article{Phan2013CorticolimbicBR,
  title={Corticolimbic brain reactivity to social signals of threat before and after sertraline treatment in generalized social phobia.},
  author={K. Luan Phan and Emil F. Coccaro and Michael Angstadt and K Jane Kreger and Helen S. Mayberg and Israel Liberzon and Murray B. Stein},
  journal={Biological psychiatry},
  year={2013},
  volume={73 4},
  pages={329-36}
}
BACKGROUND Generalized social phobia (gSP), also known as generalized social anxiety disorder, is characterized by excessive fear of scrutiny by others and pervasive avoidance of social interactions. Pathophysiologic models of gSP implicate exaggerated reactivity of the amygdala and insula in response to social evaluative threat, making them plausible targets for treatment. Although selective serotonin reuptake inhibitor (SSRI) treatment is known to be an effective treatment, little is known… CONTINUE READING
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