Corticalization of motor control in humans is a consequence of brain scaling in primate evolution

  title={Corticalization of motor control in humans is a consequence of brain scaling in primate evolution},
  author={S. Herculano-Houzel and J. Kaas and R. de Oliveira-Souza},
  journal={Journal of Comparative Neurology},
Control over spinal and brainstem somatomotor neurons is exerted by two sets of descending fibers, corticospinal/pyramidal and extrapyramidal. Although in nonhuman primates the effect of bilateral pyramidal lesions is mostly limited to an impairment of the independent use of digits in skilled manual actions, similar injuries in humans result in the locked‐in syndrome, a state of mutism and quadriplegia in which communication can be established only by residual vertical eye movements. This… Expand
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