Cortical thinning in subcortical vascular dementia with negative 11C-PiB PET.

@article{Kim2012CorticalTI,
  title={Cortical thinning in subcortical vascular dementia with negative 11C-PiB PET.},
  author={Chi Hun Kim and Sang Won Seo and Geon Ha Kim and Ji Hoon Shin and Hanna Hye-Na Cho and Young Ook Noh and Suk-Hui Kim and Min Kim and Seun Jeon and Uicheul Yoon and Jong-Min Lee and Seung Jun Oh and Jae Seung Kim and Sung Tae Kim and Jae-Hong Lee and Duk L. Na},
  journal={Journal of Alzheimer's disease : JAD},
  year={2012},
  volume={31 2},
  pages={315-23}
}
To determine the existence of cortical thinning in subcortical vascular dementia (SVaD) with a negative 11C-Pittsburgh compound B (PiB) positron emission tomography scan and to compare the topography of cortical thinning between PiB-negative SVaD and Alzheimer's disease (AD), we enrolled 24 patients with PiB(-) SVaD, 81 clinically probable AD individuals, and 72 normal cognitive controls. Compared with controls, cortical thinning in PiB(-) SVaD was most profound in the perisylvian area, medial… CONTINUE READING