Cortical thinning explains changes in sleep slow waves during adulthood.

  title={Cortical thinning explains changes in sleep slow waves during adulthood.},
  author={Jonathan W Dube and Marjolaine Lafortune and Christophe Bedetti and Maude Bouchard and Jean François Gagnon and Julien Doyon and Alan C. Evans and Jean-Marc Lina and Julie Carrier},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={35 20},
Sleep slow waves (SWs) change considerably throughout normal aging. In humans, SWs are generated and propagate on a structural backbone of highly interconnected cortical regions that form most of the default mode network, such as the insula, cingulate cortices, temporal lobe, parietal lobe, and medial frontal lobe. Regions in this network undergo cortical thinning and breakdown in structural and functional connectivity over the course of normal aging. In this study, we investigated how changes… CONTINUE READING
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