Cortical thickness reduction in individuals at ultra-high-risk for psychosis.

  title={Cortical thickness reduction in individuals at ultra-high-risk for psychosis.},
  author={Wi Hoon Jung and June Sic Kim and Joon Hwan Jang and Jung-Seok Choi and Myung Hun Jung and Ji-Young Park and Ji Yeon Han and Chi-Hoon Choi and Do-Hyung Kang and Chun Kee Chung and Jun Soo Kwon},
  journal={Schizophrenia bulletin},
  volume={37 4},
Although schizophrenia is characterized by gray matter (GM) abnormalities, particularly in the prefrontal and temporal cortices, it is unclear whether cerebral cortical GM is abnormal in individuals at ultra-high-risk (UHR) for psychosis. We addressed this issue by studying cortical thickness in this group with magnetic resonance imaging (MRI). We measured cortical thickness of 29 individuals with no family history of psychosis at UHR, 31 patients with schizophrenia, and 29 healthy matched… 

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