Cortical thickness and voxel-based morphometry in depressed elderly.

  title={Cortical thickness and voxel-based morphometry in depressed elderly.},
  author={P. C{\'e}dric M. P. Koolschijn and Neeltje E.M . van Haren and Hugo G. Schnack and Joost Janssen and Hilleke E. Hulshoff Pol and Ren{\'e} S. Kahn},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  volume={20 6},
This is the first study to examine concurrently cortical thickness and voxel-based morphometric (VBM) abnormalities in patients with major depressive disorder (MDD). In the current study we set out to investigate depressed elderly patients to determine whether a previous depression is related to neurobiological abnormalities in older age. Cortical thickness measures and VBM were applied to the same magnetic resonance imaging data set of 28 female elderly subjects with MDD and 38 age-matched… CONTINUE READING


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