Cortical spreading depression modulates the caudate nucleus activity.

  title={Cortical spreading depression modulates the caudate nucleus activity.},
  author={Masoumeh Seghatoleslam and Maryam Khaleghi Ghadiri and Nikoo Ghaffarian and E. J. Speckmann and Ali Gorji},
Cortical spreading depression (CSD) plays an important role in migraine with aura. The caudate nucleus has crucial functional interactions with brain regions likely to be important in migraine. The aim of the present in vitro study was to investigate the effect of CSD on the neuronal activity of the caudate. Intracellular recording was performed in the head of the caudate nucleus alongside of extracellular recording in Wistar rat somatosensory cortex. CSD was induced by local KCl injection… CONTINUE READING
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