Cortical spreading depression in the gyrencephalic feline brain studied by magnetic resonance imaging.

@article{James1999CorticalSD,
  title={Cortical spreading depression in the gyrencephalic feline brain studied by magnetic resonance imaging.},
  author={Michael F. James and Martin I Smith and Kurt H. J. Bockhorst and Laurance D. Hall and Gavin C. Houston and Nikolas G Papadakis and Justin M Smith and Alan R. Williams and D Xing and Andrew A. Parsons and Christopher L.-H. Huang and Thomas Adrian Carpenter},
  journal={The Journal of physiology},
  year={1999},
  volume={519 Pt 2},
  pages={415-25}
}
1.Time-lapse diffusion-weighted magnetic resonance imaging (DWI) was used to detect and characterize complex waves of cortical spreading depression (CSD) evoked with KCL placed upon the suprasylvian gyrus of anaesthetized cats. 2. The time-lapse representations successfully demonstrated primary CSD waves that propagated with elliptical wavefronts selectively over the ipsilateral cerebral hemispheres with a velocity of 3.8 +/- 0.70 mm min(-1) (mean +/- S.E.M. of 5 experiments). 3. In contrast… CONTINUE READING

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