Cortical microinfarcts and demyelination significantly affect cognition in brain aging.

@article{Kvari2004CorticalMA,
  title={Cortical microinfarcts and demyelination significantly affect cognition in brain aging.},
  author={E K{\"o}vari and Gabriel Gold and François R Herrmann and Alessandra Canuto and Patrick R. Hof and J Michel and Constantin Bouras and Panteleimon Giannakopoulos},
  journal={Stroke},
  year={2004},
  volume={35 2},
  pages={410-4}
}
BACKGROUND AND PURPOSE Microvascular lesions are common in brain aging, but their clinical impact is debated. Methodological problems such as the masking effect of concomitant pathologies may explain discrepancies among previous studies. To evaluate the cognitive consequences of such lesions, we prospectively investigated elderly individuals with various degrees of cognitive impairment but without significant neurofibrillary tangle pathology or macrovascular lesions. METHODS This was a… CONTINUE READING
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