Cortical magnetic stimulation in amyotrophic lateral sclerosis.

  title={Cortical magnetic stimulation in amyotrophic lateral sclerosis.},
  author={A. Eisen and W Shytbel and Kevin Murphy and Maureen Hoirch},
  journal={Muscle & nerve},
  volume={13 2},
Forty patients with ALS underwent cortical magnetic stimulation. Twelve had marked pseudobulbar signs; in these motor evoked potentials (MEPs) could not be elicited. Mean MEP latencies in the others, who had predominantly lower motor neuron signs, measured 23.3 +/- 2.1 msec (thenar), 18.7 +/- 5.3 msec (EDC), and 13.4 +/- 2.9 msec (biceps), respectively. These values were significantly longer (P greater than 0.001) compared with normal values (n = 35), which measured 20.2 +/- 1.6, 14.2 +/- 1.7… CONTINUE READING
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