Cortical magnetic resonance imaging findings in familial pediatric bipolar disorder.

  title={Cortical magnetic resonance imaging findings in familial pediatric bipolar disorder.},
  author={Kiki D. Chang and Naama Barnea-Goraly and Asya Karchemskiy and Diana Iorgova Simeonova and Patrick Barnes and Terence A. Ketter and Allan L. Reiss},
  journal={Biological psychiatry},
  volume={58 3},
BACKGROUND Morphometric magnetic resonance imaging (MRI) studies of pediatric bipolar disorder (BD) have not reported on gray matter volumes but have reported increased lateral ventricular size and presence of white matter hyperintensities (WMH). We studied gray matter volume, ventricular-to-brain ratios (VBR), and number of WMH in patients with familial, pediatric BD compared with control subjects. METHODS Twenty subjects with BD (aged 14.6 +/- 2.8 years; 4 female) according to the… CONTINUE READING


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