Cortical local circuit axons do not mature after early deafferentation.

  title={Cortical local circuit axons do not mature after early deafferentation.},
  author={J. S. McCasland and Kerry L. Bernardo and K L Probst and Thomas A. Woolsey},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  pages={1832 - 1836}
The processes underlying development, refinement, and retention of the intracortical connections critical for the function of the mammalian brain are unknown. Horseradish peroxidase-labeled fibers in mouse somatosensory barrel cortex, which is patterned like the whiskers on the contralateral face from which it receives inputs, were evaluated by automated image analysis. The sensory nerve to the whiskers was sectioned on postnatal day 7, after the whisker map is set. The deprived barrel cortices… 

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