Cortical excitability and age-related volumetric MRI changes

  title={Cortical excitability and age-related volumetric MRI changes},
  author={Lisa C. Silbert and Christine Nelson and Susan Holman and Ryan Eaton and James A. Kaye},
  journal={Clinical Neurophysiology},
OBJECTIVE Normative data on transcranial magnetic stimulation (TMS)-derived measures of cortical excitability in the elderly is sparse. Nevertheless, elderly subjects are included as controls in studies utilizing TMS to investigate disease states. Age-associated increased ventricular cerebrospinal fluid CSF (vCSF) and white matter hyperintensity (WMH) MRI volumes have uncertain significance in non-demented elderly. Information regarding cortical excitability in neurologically intact elderly… CONTINUE READING


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