Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos.

Abstract

In asymmetrically dividing cells, a failure to coordinate cell polarity with the site of cell division can lead to cell fate transformations and tumorigenesis. Cell polarity in C. elegans embryos is defined by PAR proteins, which occupy reciprocal halves of the cell cortex. During asymmetric division, the boundary between the anterior and posterior PAR… (More)
DOI: 10.1242/dev.040436

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@article{Schenk2010CorticalDC, title={Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos.}, author={Christian Schenk and Henrik Bringmann and Anthony A. Hyman and Carrie R. Cowan}, journal={Development}, year={2010}, volume={137 10}, pages={1743-53} }