Cortical depth-dependent temporal dynamics of the BOLD response in the human brain.

@article{Siero2011CorticalDT,
  title={Cortical depth-dependent temporal dynamics of the BOLD response in the human brain.},
  author={Jeroen C. W. Siero and Natalia Petridou and Johannes M. Hoogduin and Peter R. Luijten and Nick F. Ramsey},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2011},
  volume={31 10},
  pages={
          1999-2008
        }
}
Recent animal studies at high field have shown that blood oxygen level-dependent (BOLD) contrast can be specific to the laminar vascular architecture of the cortex, by differences in its temporal dynamics in reference to cortical depth. In this study, we characterize the temporal dynamics of the hemodynamic response (HDR) across cortical depth in the human primary motor and visual cortex, at 7 T and using very short stimuli and with high spatial and temporal resolution. We find that the shape… CONTINUE READING
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