Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging.

@article{Petrella2007CorticalDI,
  title={Cortical deactivation in mild cognitive impairment: high-field-strength functional MR imaging.},
  author={Jeffrey R. Petrella and Lihong Wang and Sriyesh Krishnan and Melissa Jane Slavin and Steven E. Prince and Thanh-Thu T Tran and P. Murali Doraiswamy},
  journal={Radiology},
  year={2007},
  volume={245 1},
  pages={224-35}
}
PURPOSE To prospectively identify brain regions in which task-related changes in activation during a memory encoding task, measured with functional magnetic resonance (MR) imaging, correlate with degree of memory impairment across Alzheimer disease (AD), mild cognitive impairment (MCI), and elderly control subjects. MATERIALS AND METHODS The institutional review board approved this HIPAA-compliant study, and each patient gave written informed consent. Seventy-five subjects (mean age, 72.9… CONTINUE READING
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