Cortical cell orientation selectivity fails to develop in the absence of ON-center retinal ganglion cell activity.

@article{Chapman2000CorticalCO,
  title={Cortical cell orientation selectivity fails to develop in the absence of ON-center retinal ganglion cell activity.},
  author={Barbara Chapman and I. G{\"o}decke},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2000},
  volume={20 5},
  pages={1922-30}
}
Neuronal activity is necessary for the normal development of visual cortical cell receptive fields. When neuronal activity is blocked, cortical cells fail to develop normal ocular dominance and orientation selectivity. Patterned activity has been shown to play an instructive, rather than merely permissive, role in the segregation of geniculocortical afferents into ocular dominance columns. To test whether normal patterns of activity are necessary to instruct the development of cortical… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Physiological segregation of ocular dominance columns depends on the pattern of afferent electrical activ

  • MP Stryker, SL Strickland
  • Invest Opthalmol Vis Sci
  • 1984
Highly Influential
5 Excerpts

Physiological segregation of ocular dominance columns depends on the pattern of afferent electrical activity

  • MP Stryker, SL Strickland
  • Invest Opthalmol Vis Sci [Suppl]
  • 1984
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…