Cortical bone regeneration with a synthetic cell-binding peptide: a histologic and histomorphometric pilot study.

@article{Scarano2003CorticalBR,
  title={Cortical bone regeneration with a synthetic cell-binding peptide: a histologic and histomorphometric pilot study.},
  author={Antonio Scarano and Giovanna Iezzi and Giovanna Petrone and Giovanna Orsini and Marco Degidi and Rita Strocchi and Adriand Piattelli},
  journal={Implant dentistry},
  year={2003},
  volume={12 4},
  pages={318-24}
}
PepGen P-15 is a combination natural anorganic bovine-derived hydroxyapatite matrix (ABM) coupled with a synthetic cell-binding peptide (P-15). This material has been reported to enhance bone formation in periodontal osseous defects. The aim of this study was to assess the effect of ABM/P-15 on the healing of cortical bone defects in rabbits. Five New Zealand rabbits were used. Two 8-mm bone defects were created in each tibia. Eight defects were filled with PepGen P-15, 8 defects with PepGen P… CONTINUE READING

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