Cortical and trabecular bone density in X-linked hypophosphatemic rickets.

  title={Cortical and trabecular bone density in X-linked hypophosphatemic rickets.},
  author={Moira S. Cheung and Paul Roschger and Klaus Klaushofer and Louis-Nicolas Veilleux and Peter J. Roughley and Francis H Glorieux and Frank Rauch},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={98 5},
CONTEXT X-linked hypophosphatemic rickets is caused by mutations in PHEX. Even though the disease is characterized by disordered skeletal mineralization, detailed bone densitometric studies are lacking. OBJECTIVE The aim of the study was to assess volumetric bone mineral density (vBMD) in X-linked hypophosphatemic rickets using forearm peripheral quantitative computed tomography. SETTING The study was conducted in the metabolic bone clinic of a pediatric orthopedic hospital. PATIENTS… CONTINUE READING


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biopsies of children , adolescents and young adults

  • PJ Marie, FH Glorieux
  • 2009

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