• Biology, Medicine
  • Published in
    The American journal of…
    1991

Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer's disease.

@article{Masliah1991CorticalAS,
  title={Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer's disease.},
  author={Eliezer Masliah and Robert D. Terry and Michael Alford and Richard M. DeTeresa and Lawrence A. Hansen},
  journal={The American journal of pathology},
  year={1991},
  volume={138 1},
  pages={
          235-46
        }
}
Quantification of synaptophysinlike immunoreactivity is a valuable method for studying the presynaptic terminals in the normal and damaged nervous system. The present report shows that in the control brain, the predominant pattern of synaptic immunostaining in the neocortex was that of an evenly distributed densely granular immunolabeling of the neuropil, while in the paleocortex and in subcortical areas of the brain most of the presynaptic terminals were distributed along the dendritic… CONTINUE READING

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