Cortical actin dynamics driven by formins and myosin V.

  title={Cortical actin dynamics driven by formins and myosin V.},
  author={Jerry Haochen Yu and Alvaro H Crevenna and Mario Bettenb{\"u}hl and Tina Freisinger and Roland Wedlich-S{\"o}ldner},
  journal={Journal of cell science},
  volume={124 Pt 9},
Cell morphogenesis requires complex and rapid reorganization of the actin cytoskeleton. The budding yeast Saccharomyces cerevisiae is an invaluable model system for studying molecular mechanisms driving actin dynamics. Actin cables in yeast are formin-generated linear actin arrays that serve as tracks for directed intracellular transport by type V myosins. Cables are constantly reorganized throughout the cell cycle but the molecular basis for such dynamics remains poorly understood. By… CONTINUE READING
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