Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases.

@article{Ruffmann2016CorticalLB,
  title={Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases.},
  author={Claudio Ruffmann and Federico Corrado Fulceri Calboli and Ilaria Bravi and Djordje Gveri{\'c} and Lisa K. Curry and Adam J de Smith and Susana Elisa Pavlou and Jessica L. Buxton and Alexandra I. F. Blakemore and Petros Takousis and Sophie Molloy and Paola P Piccini and David T Dexter and Federico Roncaroli and S M Gentleman and Lefkos T. Middleton},
  journal={Neuropathology and applied neurobiology},
  year={2016},
  volume={42 5},
  pages={
          436-50
        }
}
AIMS Our main objective was to determine the neuropathological correlates of dementia in patients with Lewy body disease (LBD). Furthermore, we used data derived from clinical, neuropathological and genetic studies to investigate boundary issues between Dementia with Lewy bodies (DLB) and Parkinson's disease with (PDD) and without (PDND) dementia. METHODS One hundred and twenty-one cases with a neuropathological diagnosis of LBD and clinical information on dementia status were included in the… CONTINUE READING
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