Cortical Information Processing in Coma

@article{Daltrozzo2009CorticalIP,
  title={Cortical Information Processing in Coma},
  author={J{\'e}r{\^o}me Daltrozzo and Norma Wioland and V{\'e}ronique Mutschler and Philippe Lutun and Bartholomeus Calon and Alaina Meyer and Thierry Pottecher and Simone Lang and Albert Jaeger and Boris Kotchoubey},
  journal={Cognitive and Behavioral Neurology},
  year={2009},
  volume={22},
  pages={53-62}
}
ObjectivesTo evaluate cortical information processing (particularly, semantic processing) in acute nontraumatic coma by means of event-related brain potentials (ERPs). MethodsThe tests included measures of obligatory auditory processing (N100), automatic (Mismatch Negativity) and controlled (P300) detection of stimulus deviance, and semantic processing (ERP effects in word pairs and sentences). The tests were presented to 20 healthy participants and 42 coma patients with Glasgow Coma Scale <9… Expand
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TLDR
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TLDR
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TLDR
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PRESERVED NEURAL FUNCTIONS IN POST-ANOXIC COMA AND THEIR ADDED VALUE FOR THE PREDICTION OF COGNITIVE AND FUNCTIONAL OUTCOME
TLDR
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Progression of auditory discrimination based on neural decoding predicts awakening from coma.
TLDR
Electroencephalography responses based on a multivariate decoding algorithm that automatically quantifies neural discrimination at the single patient level show evidence of intact auditory processing even in comatose patients who do not survive and that progression of sound discrimination over time is informative of a patient's chance of survival. Expand
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