Cortexolone 17α‐propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double‐blind comparative study vs. placebo and tretinoin 0·05% cream

@article{Trifu2011Cortexolone11,
  title={Cortexolone 17$\alpha$‐propionate 1\% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double‐blind comparative study vs. placebo and tretinoin 0·05\% cream},
  author={Viorel Trifu and George Sonn Tiplica and E Naumescu and L Zalupca and Luigi Moro and Giuseppe Celasco},
  journal={British Journal of Dermatology},
  year={2011},
  volume={165}
}
Background  Acne vulgaris is a disorder of the pilosebaceous unit in which the androgens contribute to its onset and persistence. The use of antiandrogens is therefore potentially effective; however, antiandrogens for topical use are not available on the market. Cortexolone 17α‐propionate (CB‐03‐01; Cosmo S.p.A, Lainate, Italy) is a new potent topical antiandrogen potentially useful in acne vulgaris. 
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