Correlative light and electron microscopy using immunolabeled resin sections.

@article{Schwarz2007CorrelativeLA,
  title={Correlative light and electron microscopy using immunolabeled resin sections.},
  author={Heinz J. Schwarz and Bruno Martin Humbel},
  journal={Methods in molecular biology},
  year={2007},
  volume={369},
  pages={229-56}
}
In correlative microscopy, light microscopy provides the overview and orientation in the complex cells and tissue, whereas electron microscopy offers the detailed localization and correlation to subcellular structures. In this chapter, we offer the detailed high-quality electron microscopical preparation methods for the optimum preservation of the cellular ultrastructure. From such preparations, serial thin sections are collected and used for comparative histochemical, immunofluorescence, and… CONTINUE READING