Correlative light and electron microscopy in parasite research.

@article{Loussert2012CorrelativeLA,
  title={Correlative light and electron microscopy in parasite research.},
  author={C{\'e}line Loussert and Claire-Lise Forestier and Bruno Martin Humbel},
  journal={Methods in cell biology},
  year={2012},
  volume={111},
  pages={59-73}
}
The interaction of a parasite and a host cell is a complex process, which involves several steps: (1) attachment to the plasma membrane, (2) entry inside the host cell, and (3) hijacking of the metabolism of the host. In biochemical experiments, only an event averaged over the whole cell population can be analyzed. The power of microscopy, however, is to investigate individual events in individual cells. Therefore, parasitologists frequently perform experiments with fluorescence microscopy… CONTINUE READING

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