Correlative analysis of CINtec P16 and detection of HPV DNA by PCR in cervical abnormalities

@inproceedings{Khan2011CorrelativeAO,
  title={Correlative analysis of CINtec P16 and detection of HPV DNA by PCR in cervical abnormalities},
  author={Sehaam Khan and Cd Izaaks and Ernest J Truter},
  year={2011}
}
Background The prognostic value of cervical aberrancies cannot be adequately determined by the Pap smear alone. Detection of HPV DNA by polymerase chain reaction (PCR) improves the diagnostic sensitivity however, it lacks sufficient specificity. Biomarkers that demonstrate the power to identify progressive cervical lesions may enhance the accuracy of Pap smear screening. The objective of this study is to investigate the relationship between P16 expression and HPV DNA in cervical smears, and the… CONTINUE READING

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