Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters.

@article{Kanda2008CorrelationsOT,
  title={Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters.},
  author={Mitsuro Kanda and Shuji Nomoto and Yoko Nishikawa and Hiroaki Sugimoto and Naohito Kanazumi and Shin Takeda and Akimasa Nakao},
  journal={Journal of surgical oncology},
  year={2008},
  volume={98 3},
  pages={190-6}
}
BACKGROUND The vascular endothelial growth factor (VEGF) is involved in the growth of cancer cells through angiogenesis. At present the role of VEGF-B has not been clarified completely. We investigated correlations of the expression of VEGF-B and its isoforms, VEGF-B167 and VEGF-B186, by alternative splicing in hepatocellular carcinoma (HCC) with the pathological findings and prognosis. METHODS Forty-eight patients with HCC were investigated. We examined the mRNA expression of total VEGF-B… CONTINUE READING