Correlations of inflammatory gene pathways, corticolimbic functional activities, and aggression in pediatric bipolar disorder: A preliminary study

@article{Barzman2014CorrelationsOI,
  title={Correlations of inflammatory gene pathways, corticolimbic functional activities, and aggression in pediatric bipolar disorder: A preliminary study},
  author={Drew Barzman and Jim Eliassen and Robert McNamara and Pablo Abonia and Ping-I Lin},
  journal={Psychiatry Research: Neuroimaging},
  year={2014},
  volume={224},
  pages={107-111}
}
The mechanisms underlying aggression in adolescents with bipolar disorder have been poorly understood. The present study has investigated the associations among TNF gene expressions, functional brain activations under the frustrative non-reward task, and aggression in adolescents with bipolar disorder. Baseline gene expressions and aggressive tendencies were measured with the RNA-sequencing and Brief Rating of Aggression by Children and Adolescents (BRACHA), respectively. Our results show that… CONTINUE READING

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