Correlations between photoactivable porphyrins' fluorescence, erythema and the pain induced by PDT on normal skin using ALA-derivatives.

@article{Barge2013CorrelationsBP,
  title={Correlations between photoactivable porphyrins' fluorescence, erythema and the pain induced by PDT on normal skin using ALA-derivatives.},
  author={J{\'e}r{\^o}me Barge and Thomas M Glanzmann and Matthieu P E Zellweger and D. von Salomon and Hubert E van den Bergh and Georges Wagni{\`e}res},
  journal={Photodiagnosis and photodynamic therapy},
  year={2013},
  volume={10 4},
  pages={683-93}
}
BACKGROUND Photodynamic therapy (PDT) with precursors of photoactivable porphyrins is a well-established treatment modality for skin pathologies as well as hair removal. Pain is a major side effect thereof, and it affects the treatment compliance and acceptance. METHODS Five male subjects underwent a PDT procedure on normal skin, either with a diode laser (635 nm) or a lamp (405 nm), 3 or 6h after application of various precursors of photoactivable porphyrins (ALA 1M; Metvix(®) 1M; ALA-DGME… CONTINUE READING