Correlations between long inverted repeat (LIR) features, deletion size and distance from breakpoint in human gross gene deletions

@inproceedings{Aygun2015CorrelationsBL,
  title={Correlations between long inverted repeat (LIR) features, deletion size and distance from breakpoint in human gross gene deletions},
  author={Nevim Aygun},
  booktitle={Scientific reports},
  year={2015}
}
Long inverted repeats (LIRs) have been shown to induce genomic deletions in yeast. In this study, LIRs were investigated within ±10 kb spanning each breakpoint from 109 human gross deletions, using Inverted Repeat Finder (IRF) software. LIR number was significantly higher at the breakpoint regions, than in control segments (P < 0.001). In addition, it was… CONTINUE READING