Correlation of tumor volume and surface area with lymph node status in patients with multifocal/multicentric breast carcinoma.

@article{Andea2004CorrelationOT,
  title={Correlation of tumor volume and surface area with lymph node status in patients with multifocal/multicentric breast carcinoma.},
  author={Aleodor Andea and David L. Bouwman and Tracie Wallis and Daniel W. Visscher},
  journal={Cancer},
  year={2004},
  volume={100 1},
  pages={20-7}
}
BACKGROUND Multicentric breast carcinomas have a higher frequency of axillary lymph node metastasis than unifocal tumors of similar stage. It remains unclear whether this merely reflects larger tumor volumes or a different biologic behavior. The authors have shown previously that when aggregate tumor diameter are used for staging, unifocal and multifocal tumors have a similar frequency of axillary lymph node metastasis. However, summing diameter overestimates actual tumor volume because volume… CONTINUE READING