Correlation of serum interleukin-8 and cell surface lysosome-associated membrane protein expression with clinical disease activity in systemic lupus erythematosus.

@article{Holcombe1994CorrelationOS,
  title={Correlation of serum interleukin-8 and cell surface lysosome-associated membrane protein expression with clinical disease activity in systemic lupus erythematosus.},
  author={Randall F. Holcombe and Bruce A. Baethge and Robert E. Wolf and Kenneth W. Betzing and R. M. Stewart and V C Hall and Minoru Fukuda},
  journal={Lupus},
  year={1994},
  volume={3 2},
  pages={97-102}
}
Cell surface expression of lysosome-associated membrane proteins (LAMPs) correlates with serum interleukin-8 (IL-8) levels, shorter disease duration, greater functional impairment from disease-related symptoms and soluble IL-2 receptor levels (sIL-2R) in patients with scleroderma. In this study of 46 patients with systemic lupus erythematosus (SLE), the relationship of serum IL-8 and cell surface LAMP to two clinical measures of disease activity, the SLEDAI and SLAM scales, was evaluated. IL-8… CONTINUE READING