Correlation of organism burden and alveolar macrophage counts during infection with Pneumocystis carinii and recovery.

@article{Lasbury2003CorrelationOO,
  title={Correlation of organism burden and alveolar macrophage counts during infection with Pneumocystis carinii and recovery.},
  author={Mark E. Lasbury and Pamela J. Durant and Marilyn S. Bartlett and J. Weston Smith and Chao-Hung Lee},
  journal={Clinical and diagnostic laboratory immunology},
  year={2003},
  volume={10 2},
  pages={
          293-302
        }
}
Changes in the number of alveolar macrophages were correlated with organism burden during Pneumocystis carinii infection. The lungs of healthy, dexamethasone-treated, and dexamethasone-treated and P. carinii-infected rats were lavaged with phosphate-buffered saline. Counting of alveolar macrophages in the lavage fluids revealed that P. carinii infection caused a 58% decrease in the number of alveolar macrophages and that higher P. carinii organism burdens caused a more rapid decrease in… CONTINUE READING

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