Correlation of metallothionein expression with apoptosis in nasopharyngeal carcinoma

  title={Correlation of metallothionein expression with apoptosis in nasopharyngeal carcinoma},
  author={Anita Jayasurya and Boon-Huat Bay and W M Yap and N G Tan},
  journal={British Journal of Cancer},
  pages={1198 - 1203}
The expression of metallothionein (MT), an intracellular ubiquitous low molecular weight protein thiol with antioxidant properties, was studied in nasopharyngeal cancer (NPC) and correlated with the apoptotic index. Immunohistochemical staining of randomly selected, formalin-fixed and paraffin-embedded normal and malignant nasopharyngeal tissues were analysed for the expression of MT using the commercially available E9 antibody directed against MT I and MT II isoforms. The corresponding… CONTINUE READING
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