Effectiveness and safety of aflibercept for metastatic colorectal cancer: retrospective review within an early access program in Spain.
- J Feliu, I Díez de Corcuera, +5 authors J Sastre
- Clinical & translational oncology : official…
- 2017
1 Excerpt
Correlation of lactate dehydrogenase isoenzyme profile with outcome in patients with advanced colorectal cancer treated with chemotherapy and bevacizumab or cediranib: Retrospective analysis of the HORIZON I study.
- Published 2014 in Clinical colorectal cancer
Abstract
INTRODUCTION
Bevacizumab improves outcome for patients with advanced colorectal cancer (CRC) when added to chemotherapy. The HORIZON I trial resulted in similar outcome with bevacizumab or cediranib, a small-molecule tyrosine kinase inhibitor of vascular endothelial growth factor (VEGF) receptor, as treatment of advanced CRC. The spectrum of lactate… (More)