Correlation of karyotype with clinical features in acute lymphoblastic leukemia.

@article{Kaneko1982CorrelationOK,
  title={Correlation of karyotype with clinical features in acute lymphoblastic leukemia.},
  author={Yasuhiko Kaneko and Janet D. Rowley and Daina Variakojis and Robert R. Chilcote and Irene J. Check and Masaharu Sakurai},
  journal={Cancer research},
  year={1982},
  volume={42 7},
  pages={2918-29}
}
We studied the clinical and karyotypic features of 50 patients with acute lymphoblastic leukemia, including 33 American and 17 Japanese patients, at two institutions. Clonal chromosome abnormalities were found in 39 of the 50 patients (78%) at diagnosis. Eleven patients had diploidy (N patients). Among the 39 aneuploid patients, 17 had pseudodiploidy (A1 patients), eight had hyperdiploidy with 47 to 49 chromosomes (A2 patients), nine had hyperdiploidy with 50 to 59 chromosomes (A3 patients… CONTINUE READING

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