Correlation of in vitro properties of Rhodococcus (Corynebacterium) equi with virulence for mice.

@article{Takai1985CorrelationOI,
  title={Correlation of in vitro properties of Rhodococcus (Corynebacterium) equi with virulence for mice.},
  author={Shinji Takai and T Michizoe and Kenji Matsumura and Masaaki Nagai and Hanako Sato and Shiro Tsubaki},
  journal={Microbiology and immunology},
  year={1985},
  volume={29 12},
  pages={1175-84}
}
To study the virulence of Rhodococcus (Corynebacterium) equi, seven ATCC strains of different serotypes were tested for their LD50 in mice, clearance of the organism from the lungs and spleen following intravenous or intratracheal inoculation, and in vitro interaction with murine peritoneal macrophages. Strains ATCC 33704 and 33705 were virulent for mice and multiplied in the lungs and spleen, resulting in death of the animal in 5 days. The other five strains were avirulent for mice. The number… CONTINUE READING