Correlation of hypoxia inducible transcription factor in breast cancer and SUVmax of F-18 FDG PET/CT.

  title={Correlation of hypoxia inducible transcription factor in breast cancer and SUVmax of F-18 FDG PET/CT.},
  author={Y. Jeong and Jaewon Jung and Y. Cho and Sung-Hwan Park and H. Oh and Sungmin Kang},
  journal={Nuclear medicine review. Central \& Eastern Europe},
  volume={20 1},
BACKGROUND Tumor hypoxia induces the expression of several genes via the hypoxia-inducible transcription factor-1 alpha (HIF-1a). It is associated with the prognosis of several cancers. We studied the immunohistochemical expression of HIF-1a in patients with invasive ductal cancer (IDC) of the breast and the possible correlation with the maximum standardized uptake value of the primary tumor (pSUVmax) as well as other biological parameters. Prognostic significance of pSUVmax and expression of… Expand
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Current insights and future perspectives of hypoxia-inducible factor-targeted therapy in cancer
  • T. Ajith
  • Biology, Chemistry
  • Journal of basic and clinical physiology and pharmacology
  • 2018
Hypoxia Mediates Tumor Malignancy and Therapy Resistance.


Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis.
Prognostic Value of Primary Tumor Uptake on F-18 FDG PET/CT in Patients with Invasive Ductal Breast Cancer
Differential prognostic impact of hypoxia induced and diffuse HIF-1α expression in invasive breast cancer
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Hypoxia-Induced increase in FDG uptake in MCF7 cells.
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