Correlation of human in vivo and in vitro cutaneous antimicrobial factors.

@article{Aly1975CorrelationOH,
  title={Correlation of human in vivo and in vitro cutaneous antimicrobial factors.},
  author={R. R. Aly and Howard Ira Maibach and Rubina Rahman and Henry R. Shinefield and Adrian D. Mandel},
  journal={The Journal of infectious diseases},
  year={1975},
  volume={131 5},
  pages={
          579-83
        }
}
the presence of antimicrobial substances on human skin was investigated. Staphyloccus aureus (10-4 colony-forming units) was applied on the forearm of 50 subjects and covered with a semiocclusive device for 24 hr. In 54% of the subjects the organisms persisted, and in 34% S. aureus was inhibited on the skin. Subjects with persistent S. aureus also had persistent Candida albicans, and vice persa. This correlation was not noted with Streptococcus pyogenes. Skin lipids from the two groups of… CONTINUE READING
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