Correlation of histopathological features and proliferative potential of gliomas.

  title={Correlation of histopathological features and proliferative potential of gliomas.},
  author={Isabelle M Germano and Masahiro Ito and Kyung G. Cho and Takao Hoshino and Richard L. Davis and Charles Bo Wilson},
  journal={Journal of neurosurgery},
  volume={70 5},
One hundred fifty-two intracranial gliomas of various types were reviewed in order to correlate the histopathological features with the proliferative potential of each tumor as reflected by the bromodeoxyuridine (BUdR) labeling index (LI). Patients undergoing surgical removal of gliomas were given a 30-minute intravenous infusion of BUdR (150 to 200 mg/sq m) to label S-phase tumor cells. The tumor specimens were stained immunohistochemically for BUdR and processed for routine histopathological… CONTINUE READING
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