Correlation of cavitation with ultrasound enhancement of thrombolysis.

@article{Datta2006CorrelationOC,
  title={Correlation of cavitation with ultrasound enhancement of thrombolysis.},
  author={Saurabh Datta and Constantin C Coussios and Louis E. McAdory and Jun Tan and Thomas Richard Porter and Gabrielle M. de Courten-Myers and Christy K. Holland},
  journal={Ultrasound in medicine & biology},
  year={2006},
  volume={32 8},
  pages={
          1257-67
        }
}
Pulsed ultrasound, when used as an adjuvant to recombinant tissue plasminogen activator (rt-PA), has been shown to enhance thrombolysis in the laboratory as well as in clinical trials for the treatment of ischemic stroke. The exact mechanism of this enhancement has not yet been elucidated. In this work, stable and inertial cavitation (SC and IC) are investigated as possible mechanisms for this enhancement. A passive cavitation detection scheme was utilized to measure cavitation thresholds at… CONTINUE READING
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