Correlation of blood pressure in normotensive and hypertensive individuals with platelet but not lymphocyte intracellular free calcium concentrations.

@article{Pritchard1989CorrelationOB,
  title={Correlation of blood pressure in normotensive and hypertensive individuals with platelet but not lymphocyte intracellular free calcium concentrations.},
  author={Kevin H. Pritchard and AnthonyE. G Raine and Christopher C. Ashley and Linda M. Castell and V. K. Somers and Carla N. Osborn and John Charles Grant Ledingham and James T. Conway},
  journal={Clinical science},
  year={1989},
  volume={76 6},
  pages={
          631-5
        }
}
1. Fifty-two normotensive and essential hypertensive subjects were studied. Intracellular free calcium concentration [( Ca2+]i) was measured in lymphocytes (37 subjects) and platelets (18 subjects) by means of the fluorescent indicators, quin 2 and fura-2. In 31 subjects, plasma ionized calcium concentration was also measured. 2. There was a positive correlation between platelet [Ca2+]i and systolic blood pressure (r = 0.485, P less than 0.05), diastolic blood pressure (r = 0.542, P less than 0… CONTINUE READING

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