Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL

@inproceedings{Niu2017CorrelationOB,
  title={Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL},
  author={Chenglei Niu and Sylvia Li-chun Lin and Li-Jen Yuan and Li-Huei Chen and Chuen-Yung Yang and Albert Chung and Meng-Ling Lu and Tsung-Ting Tsai and Po Liang Lai and Wen-Jer Chen},
  booktitle={BMC musculoskeletal disorders},
  year={2017}
}
BACKGROUND Wnt signaling plays an important role in development and maintenance of many organs and tissues. The most-studied secreted Wnt inhibitors are sclerostin (SOST), Dickkopf-related protein 1 (DKK-1), and secreted frizzled related protein 1 (SFRP-1) which play important roles in bone turnover. The present study investigated the relationship between serum Wnt inhibitors and diseases with excessive ossification structures, such as ossification of posterior longitudinal ligament (OPLL… CONTINUE READING
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