Correlation of anti-idiotype network with survival following anti-G(D2) monoclonal antibody 3F8 therapy of stage 4 neuroblastoma.

@article{Cheung2000CorrelationOA,
  title={Correlation of anti-idiotype network with survival following anti-G(D2) monoclonal antibody 3F8 therapy of stage 4 neuroblastoma.},
  author={Nai-Kong V Cheung and Hongfeng Guo and Irene Y. Cheung},
  journal={Medical and pediatric oncology},
  year={2000},
  volume={35 6},
  pages={635-7}
}
BACKGROUND A transient human anti-mouse antibody response was associated with significantly longer survival [Cheung et al. (1998): J Clin Oncol 16:3053] following antibody 3F8 (Ab1) treatment. We postulate that the induction of an idiotype network which included anti-anti-idiotypic (Ab3) and anti-G(D2) (Ab3') responses is associated with tumor control… CONTINUE READING