Correlation of MR imaging and MR spectroscopy findings with cognitive impairment in mucopolysaccharidosis II.

@article{Vedolin2007CorrelationOM,
  title={Correlation of MR imaging and MR spectroscopy findings with cognitive impairment in mucopolysaccharidosis II.},
  author={L M Vedolin and Ida Vanessa D Schwartz and M{\'a}rcia Koml{\'o}s and Alice Schuch and Ana Cristina Puga and Louise L C Pinto and Anna Paula Batista de {\'A}vila Pires and Roberto Giugliani},
  journal={AJNR. American journal of neuroradiology},
  year={2007},
  volume={28 6},
  pages={1029-33}
}
BACKGROUND AND PURPOSE There are no reliable markers to predict neurologic outcome of patients with mucopolysaccharidosis (MPS) II. We hypothesized that brain MR imaging and MR spectroscopy are useful in depicting features related to cognitive impairment (CI) in MPS II. MATERIALS AND METHODS Nineteen male patients with MPS II were included in this study. They were evaluated through intelligence/developmental tests to be classified in 2 groups: patients with CI (group A) or patients without CI… CONTINUE READING

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