Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (CRC).

@article{Chien2007CorrelationOK,
  title={Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (CRC).},
  author={C C Chien and Shu-Hung Chen and C E Liu and Chia-Long Lee and Ruey-Neng Yang and S H Yang and Chi-Jung Huang},
  journal={Translational research : the journal of laboratory and clinical medicine},
  year={2007},
  volume={149 2},
  pages={96-102}
}
Colorectal cancer (CRC) is the predominant gastrointestinal malignancy and constitutes a major medical and economic burden worldwide. A thorough understanding of the oncogenes or genes related to tumorigenesis is the key to developing successful therapeutic strategies. Molecular analysis of feces constitutes a potentially potent and noninvasive method for detection of CRC. Using nested reverse transcription-polymerase chain reaction (RT-PCR) and amplified restriction fragment length… CONTINUE READING

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